You can intercept the URL with modperl too, and do what you want with it. For example you can imitate that you have plenty of CGI pages (index.cgi, blahblah.cgi, etc.), and you only use it to find which function to call. Sweet, isn't it?
Or you can do http://someserver/somepath/12,45,3434,221 etc. URL's too :)

-- tune