Anyone know if the install on the Mac is similar? Did not see a Mac install up there.

Again, derby, thanks.

For mac and linux (depending on config), you just want to do:

$ sudo perl -MCPAN -eshell
cpan[1]> install DBD::SQLite
[download]

but for mac, you'll need to ensure you have the OS-X developer tools installed.
-derby

Tried doing the install on the Mac and I received:

Checking if your kit is complete...
Looks good

    I see you're using perl 5.008006 on darwin-thread-multi-2level, ok
+ay.
    Remember to actually *read* the README file!
    Use  'make' to build the software (dmake or nmake on Windows).
    Then 'make test' to execute self tests.
    Then 'make install' to install the DBI and then delete this workin
+g
    directory before unpacking and building any DBD::* drivers.

Writing Makefile for DBI
Can't exec "-j3": No such file or directory at /System/Library/Perl/5.
+8.6/CPAN.pm line 4566.
   -j3 -- NOT OK
Running make test
  Can't test without successful make
Running make install
  make had returned bad status, install seems impossible
Running make for M/MS/MSERGEANT/DBD-SQLite-1.13.tar.gz
  Is already unwrapped into directory /Users/mike/.cpan/build/DBD-SQLi
+te-1.13

  CPAN.pm: Going to build M/MS/MSERGEANT/DBD-SQLite-1.13.tar.gz

Can't exec "-j3": No such file or directory at /System/Library/Perl/5.
+8.6/CPAN.pm line 4566.
   -j3 -- NOT OK
Running make test
  Can't test without successful make
Running make install
  make had returned bad status, install seems impossible
[download]