The graphics are at 300 dpi and do not need to be resized for printing. They're about 300 of them too, and laying them out... oui! I've done it before and they can be autoplaced.

The only problem with Scribus (I've checked) and Pagemaker (Mac/Windows) is that they don't offer mass-layout of graphics. It's a comic book from a webcomic using newspaper-like formatting for the graphics. The layout's rather complicated.

Thankfully RTF is an open standard.