in reply to Emacs, cperl mode and syntax highlighting

You might try running cperl-find-pods-heres. Finding POD is supposedly expensive, so cperl avoids doing so to keep editing responsive. I have this bound to C-c C-f in cperl-mode to fix things up:
(defun my-perl-refontify () (interactive) (cperl-find-pods-heres) (font-lock-fontify-buffer))