If you are already a long-time or comfortable Perl programmer on Unix, then Strawberry Perl is going to be the most comfortable Perl for you. It's the closest thing there is to Perl on Unix.

Of course, I'm utterly biased in that regard. So instead I'll blatantly name drop.

Larry Wall uses Strawberry Perl when on Win32.

Audrey Tang uses Strawberry Perl when on Win32.

Simon Cozens uses Strawberry Perl when on Win32.

The biggest caveat is that Strawberry doesn't need binary packages, it just installs everything from CPAN like on Unix.

This means that in the limited situation you REALLY need a module that's tricky to get working on Win32 from source, the work done to package the module into a binary package will be very useful.