The user that run the script, can read the path?

Try:

Begin{
$ENV{'LD_LIBRARY_PATH'}= "/opt/instantclient_10_2/";
$ENV{'ORACLE_HOME'}= "/opt/instantclient_10_2/";
};
[download]

And show more core of your scripts.

I am calling DB connection in my code. So the PERL program trying to find the LD_LIBRARY_PATH and ORACLE_HOME.. Though I set using $ENV , the perl program is not able to find both Environment variables and giving error. If I manually set using export command , then works.