Sure. I'd use Prototype to do this. If I wanted to submit a form with two fields "foo" and "bar" to two scripts, "one.pl" and "two.pl" I'd do:

  var params = { foo: $('foo').value,
                 bar: $('bar').value };

  new Ajax.Request("one.pl", { 
                      parameters: params,
                      onSuccess: handle_one
                   });
                   
  new Ajax.Request("two.pl", { 
                      parameters: params,
                      onSuccess: handle_two
                  });
[download]

Then I'd write "handle_one()" and "handle_two()" to do something with the return values from the scripts. Also, you'll want onFailure and onException handlers. But that's the basic idea.

Reluctant JavascriptMonk,
-sam