I'd suggest that you pick from two broad choices. WordNet::SenseRelate or the less complicated approach using an exception list(freely available, just Google). The learning curve on the first is steepish and the results of the second are an '80%' solution but easy to put in place. A particularly good source of information is the journal 'Computers and the Humanities' (which may have stopped or changed names, your friendly reference librarian will know) found in most college libraries. It is almost entirely devoted to textual analysis of which a concordance is almost a beginners tool.

Second from chess software this is my favorite subject---I've always wanted to generate one for the Lord of the Rings (and related) just for grins. It was also a good way to learn IBM 360 assembler ;)!