Probably IO::Scalar would work as well. It allows you to treat a scalar as a FH object. In this case, you could grab your scalar from MySQL, sucked into a scalar, and IO::Scalar can give you a FH that you could slurp into Image::Magick.
that seems simplest to this monk, but then I love that module.
brother dep.
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Comment on Re: Image::Magick and reading images from variables.