Here's a simple test case. Empirically, if you have this:

#!/usr/bin/perl --
use strict;
use warnings;

package Foo;

sub new {
    my $self = { 'foo' => 'bar' };
    return bless $self;
}

sub DESTROY {
    print $_[0]{'foo'} . "\n";
}

package main;

my $foo = Foo->new;
exit;
[download]

then it produces this:

bar
[download]

So, as a rule I'd say yes it'll be there.

However, be sure to consider liz's comments in Re: cleaning up in DESTROY, the thread at Object reference disappearing during global destruction, and phillup's journal entry at http://use.perl.org/~phillup/journal/21827 which covers unordered global destruction as well. That appears to be a dark corner in which quite a few people find themselves. I don't think I'd call it a bug, per se, but maybe perlobj could be a little more verbose on the implications of what happens during global destruction.