That would be fine if you were trying to invoke Perl from the commandline; it won't work for a script.

ben@Tyr:~$ alias foobar="/usr/bin/perl"
ben@Tyr:~$ cat <<! >xyz
> #!foobar -w
> print \$ARGV[0]
> !
ben@Tyr:~$ chmod +x xyz
ben@Tyr:~$ ./xyz Hello
-bash: ./xyz: foobar: bad interpreter: No such file or directory
[download]

Update: Added a '\' in front '$ARGV'. It doesn't change the outcome, but it actually puts "$ARGV[0]" instead of "[0]" into 'xyz'...


-- 
Human history becomes more and more a race between education and catastrophe. -- HG Wells