If you want to compile extensions to Perl, you need to use a compiler compatible with the compiler used to compile your version of Perl. To be on the safe side, I recommend using exactly the same compiler that was used to compile your Perl to compile the extensions.

One approach could be to compile your own Perl using the VC++ express compiler and then use that for the extensions.

Another approach might be to try to reproduce what Adam Kennedy does with Strawberry Perl except for 64bit, by finding a 64bit MinGW gcc and using that to compile Perl.

Of course, as you don't tell us how things fail for you, this is all just a guess.