in reply to Re: replace fist and last occurrences of Nin thread replace fist and last occurrences of N
shell$ perl -pi.bak -le 's/(?<=[^n])n|n(?=[^n])/^/ig' yourfile.txt [download]
UPDATE: it will not work, because your file has newlines (somehow I missed it). Try this instead:
perl -pi.bak -0377 -e 's/n([n\n]*)n/^$1^/ig' yourfile.txt [download]