What I've done is:
- create a new volume that's formatted as case-sensitive HFS+
- using Perl::Install, I have my own perl install outside of any root influence
- put /Volumes/dev/perl/current/bin/ first in my path
This solves a multitude of issues that case-insensitive filesystems have and I don't mess with system perl.
My criteria for good software:
- Does it work?
- Can someone else come in, make a change, and be reasonably certain no bugs were introduced?