Describe the problem you are trying to solve. My mind reading ability is limited and somewhat spasmodic.

use strict;
use warnings;

my @hand3 = qw/KsQs JsAs/;
my @hand4 = qw/AsKc 2s3s/;
my @hand899 = qw/As3c/;

my @handsLists = (\@hand3, \@hand4, \@hand899);
##Set my hand
my $my_pocket = "AcAs";

#My cards
my %pocketCards = map {$_ => 0} $my_pocket =~ /(.{2})/g;
printf join '', keys %pocketCards, "\n\n";

for my $hands (@handsLists) {
    # If either pocket card matches the first hand card omit the hand
    @$hands = grep {! exists $pocketCards{substr ($_, 0, 2)}} @$hands;
    print "@$hands\n";
}
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Prints:

KsQs JsAs
2s3s
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I need it to say:

KsQs
2s3s
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It any of the cards in my hand are found in either of my opponents cards, then the whole hands needs to be removed from it's @hand?.

use strict;
use warnings;

my @hand3 = qw/KsQs JsAs/;
my @hand4 = qw/AsKc 2s3s/;
my @hand899 = qw/As3c/;

my @theirHands = (\@hand3, \@hand4, \@hand899);
my $myHand = "AcAs";
my %myCards = map {$_ => 0} $myHand =~ /(.{2})/g;
print "My hand: ", join '', keys %myCards, "\n";

for my $hands (@theirHands) {
    # If any of my cards match an opposing hands' card, reject the opp
+osing hand
    my @retained;

    for my $hand (@$hands) {
        next if grep {exists $myCards{$_}} $hand =~ /(.{2})/g;
        push @retained, $hand;
    }

    print "@retained\n";
}
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Prints:

My hand: AsAc
KsQs
2s3s
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