I havn't tried that many data points on a Tk or Gtk2 canvas, but I will guess that it will start to bog down, unless you break the datapoints into smaller sets, of say 1000 points, then graph them as separate bezier curve segments. See
Tk Realtime data aquisition if you are
interested. You also should look at
PDL, but I have no idea how well that works on win32, especially getting all the extra graphics output modules compiled right. The PDL maillist is full of guys that plot millions of points for space exploration, so you might want to look at it, and join in.