What is the best way to install CPAN modules on Debian? discusses some of the options for Debian. Debian uses its Perl distro as part of its OS - compunding the problem. There are also some scattered comments about Solaris, Ubuntu, RedHat, CentOS, among others (no Fedora though). Perhaps you would find it helpful.
Best, beth
Comment on Re: How to deal with distro Perl modules _and_ CPAN ?
Double Plus Plus endorsement of Beth's suggestion. The original question is written excellently and followup discussion packed with thoughtful suggestions.