It's quite easy to create your own character classes. See the section User-Defined Character Properties in the perlunicode manual page. For instance:

sub IsVowel {<<"EOT"}
041
045
049
04F
055
061
065
069
06F
075
EOT

"A" =~ /\p{IsVowel};  # Matches
"B" =~ /\p{IsVowel};  # Does not match.
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