This shows that the @INC manipulation actually had an effect this time :)

Unfortunately, the module that was found under D:\\Perl\\site\\lib apparently isn't binary compatible with your perl (most likely, the shared lib associated with the DBD part is the culprit).

Anyhow, you said it did work before. So - as the @INC manipulation cannot have had any effect before - some other module must have been found at the time (under the default lib paths)... Maybe you can reconstruct which version/build of DBI/DBD and perl that had been.  Otherwise you'll likely have to reinstall the DB modules.