The criteria to be in the list is complex (and I don't want to go off-topic). The numbers are highly constrained, yet once they make it to the list, I need to find all pairs of numbers which do not share any common bits (after getting rid of the one shared lsb). Below is an example of a valid pair. The bit-wise complement may or may not exist in the list.

#all values have been right shifted to get rid of lsb
$i1 = 0b1010_0100;
$i2 = 0b0100_1000;
#the above two numbers are a valid pair.
# yet my list may not contain either ~$i1 or ~$i2
$i1_bits_reversed = 0b0101_1011;
$i2_bits_reversed = 0b1011_0111
# the above two numbers are not a valid pair,
[download]

Yes, I see it now.

I must have misunderstood your condition "do not share any common bits" to mean ~($i1 XOR $i2) instead of $i1 & $i2. For example, the two numbers in the first example do "share" common bits in the sense that both bits are 0. In this case the only valid value for a given $i1 would be ~$i1 and nothing else.

However, if the condition is $i1 & $i2 == 0, then you're right, there are several possible $i2's.

Still, you may be still better off generating the list of possible values for every existing element of the array and check those instead of blindly doing all comparisons.