my %words = (
    score => {
        replacement => 'twenty',
        stopwords => {
            fourscore => 1,
            scored => 1,
            scores => 1,
        },
    },
    core => {
        replacement => 'center',
        stopwords => {
            encore => 1,
            coreagent => 1,
        },
    },
    centre => {
        replacement => 'center',
        stopwords => { },
    },
    ...
);
[download]

If you have the data structure above, you may have enough to construct an efficient logic needed to achieve your task.