Looking for a POE based distributed job scheduler may be helpful, as well as reading up on how POE actually works and it's requirements.

yes, but how do I serialize a sub and send it on the socket ?

Be aware that unless your sub is very trivial, you have much more to do than just serialising the sub. If that sub make use of any modules, you'll also have to arrange for those modules to be loaded and initialised at the other machine also. And if those modules use any modules...

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Umm, serializing a sub is not easy in perl as far as I know, but what about storing your sub's source as a string, send it over the socket as plain text, then eval at the other end of the socket?

my $sub_str = q{
  sub {
    my $n = shift;
    return $n + 1;
  }
};

# send the string through the socket

# at the far end of the socket:
my $sub_ref = eval $sub_str;
print $sub_ref->(2), "\n";
[download]

Put it in a module, and use a source control system. (git, hg, svn, cvs, ...)

The easy way to do this IMO would be to have your central machine turn these subroutines into simple runnable Perl scripts, and send these over the wire in text form. Then have your remote slaves execute these scripts with the appropriate input and send back the output. Whether this is an appropriate way of doing things depends on what exactly these subroutines should do and how often they are run.