Yes, IO::Compress::Zip supports Zip64 (which allows zip members to be larger than 4Gig). Here is an example of how to use it

    use IO::Compress::Zip qw(:all);

    zip [ "bigfile1", "bigfile2"] => "myzip.zip",
        Zip64 => 1
    or die "Cannot create zip file: $ZipError\n";
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IO::Uncompress::Unzip supports Zip64 as well.