in reply to script doesn't print anything

It doesn't even print any errors. Any thoughts?

I'm not sure why you chose IO::Pipe to run this, but the IO::Pipe docs show

$pipe->reader(qw(ls -l)); while(<$pipe>) { print ... }
I would think that IPC::Open3 would be more straightforward. Like this example which shows how to grab STDERR too.
#!/usr/bin/perl use warnings; use strict; use IPC::Open3; use IO::Select; my $pid = open3(\*WRITE, \*READ,\*ERROR,"/bin/bash"); my $sel = new IO::Select(); $sel->add(\*READ); $sel->add(\*ERROR); my($error,$answer)=('',''); while(1){ print "Enter command\n"; chomp(my $query = <STDIN>); #send query to bash print WRITE "$query\n"; foreach my $h ($sel->can_read) { my $buf = ''; if ($h eq \*ERROR) { sysread(ERROR,$buf,4096); if($buf){print "ERROR-> $buf\n"} } else { sysread(READ,$buf,4096); if($buf){print "$query = $buf\n"} } } } waitpid($pid, 1); # It is important to waitpid on your child process, # otherwise zombies could be created.

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