As I have commented before, the general opinion is that Lisp is bloated and slow. This opinion was formed on hardware with 1% of the memory and speed of current PC hardware.

Additionally there has beeen a lot of research into how to optimize Lisp. It turns out that Lisp can be optimized very well. If you are willing to give it the right declarations, amazingly so. Most of the ideas that people have for how to make Perl 6 optionally fast? Well Lisp had those ideas ages ago and standardized it into ANSI Common Lisp. And vendors have had years to implement it then fine tune the results...