You still don't make sense. Have you tried the OP's code? It works fine for me and (with a small tweak for counting) gives about 15,500 updates per second (not sure why the OP found that too slow actually).

use strict;
use warnings;
use Win32::GuiTest;

my $start = time;
my $times;

1 while time - 1 < $start;

while (time - 6 < $start) {
    my ($x, $y) = Win32::GuiTest::GetCursorPos();
    print "X is at $x, Y is at $y\n";
    ++$times;
}

print +($times / 5), "\n";
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