I want to know whether there is any way to pre-antialiase a given ttf file using perl..

"Pre-" to what?

To the best of my knowledge, there is no way to "pre-antialiase a given ttf file". In any language.

Anti-aliasing involves blending the color of the foreground color (the color the text is to be drawn in), with the background color (the color over which the text is to be drawn), for selected pixels to produce tha appearance of smoother curves and diagonals.

To "pre-antialias" a font, you would need to know what colors (foreground and background) the font would be drawn n before they were drawn.

In essence, your question does not make sense. Try explaining why you want to do this and what you hope to achieve by it?