One thing to investigate is wordwrapping. My app just uses the default behavior where text just disappears off the screen if column width is too small. I seem to remember a post that mentioned some trouble getting word wrap to work - so I'd definitely investigate that issue with a little prototype first - make sure your major feature works before getting too far into this.

You should also be aware that the data storage is a bit strange. TableMatrix uses a hash with keys like: "0,3" or "45,14" to indicate row 0, col 3, etc. That means that inserting a row is a hassle. I didn't do any inserts, but I did do sorts. To sort, on some combination of columns, I wound up just copying to an AoA, sort and then copy back. As it turned out even with 80,000 hash keys, the performance of this was noticeable, but "ok". I don't know what to recommend, but I'd spend some more time looking for something that would allow easier insert operations.

There is a number of tk widgets to deal with task, and tablelist widget is one of them (another alternatives could be treeview from tile package and tktable).

use strict;
use Tcl::Tk;

my $int = new Tcl::Tk;
my $mw = $int->mainwindow;

# the tablelist widget is described at
# http://docs.activestate.com/activetcl/8.5/tablelist/tablelistWidget.
+html

$int->pkg_require('tablelist');
$int->Eval('namespace import tablelist::*');

my $w_t = $mw->Scrolled('tablelist',-columns =>[0, "First Column", 0, 
+"Another column"],
         -stretch =>'all', -background =>'white')->pack(-fill=>'both',
+ -expand=>1, -side=>'top');

$w_t->columnconfigure(0, -editable=>1);
$w_t->columnconfigure(1, -editable=>1);

$w_t->insert('end', ["row $_;", "$_ bla bla"]) for 'a'..'zzz';

$int->MainLoop;
[download]

Most of this is way over my head, especially $w_t->insert('end', ["row $_;", "$_ bla bla"]) for 'a'..'zzz';. No idea what that may do.
I see your code uses Tcl::Tk, which I've never looked into. I've been playing around with Perl/Tk and implemented some very simple Tk code in the latest release of my script. I'm not sure I want to switch over to Tcl::Tk, but I can't see any mention of the tablelist widget in any Perl/Tk documentation. Tcl::Tk is supposed to be simply be another way to acces the same Tk stuff that one can use with the Tk module, so one would expect the same widgets to be available... I'm getting confused here. Well, who would be better able to clear this up than the Tcl::Tk developer, right?

I warned that my approach to Tk is a bit different :)

this line:

$w_t->insert('end', ["row $_;", "$_ bla bla"]) for 'a'..'zzz';
[download]

is rather simple, it is just looping over a list:

for my $hh ('a'..'zzz') {
  $w_t->insert('end', ["row $hh;", "$hh bla bla"]);
}
[download]

The great advantage of Tcl::Tk over perl/Tk is that in latter you have only those Tk widgets that are happen to be specially adopted for perl, plus pure-perl widgets (and this is not really much)

Tcl::Tk gives you all zoo of tcl/tk widgets and provides you with a perl/Tk syntax. It is really thin glue between perl and tcl/tk