Microcebus:

As others have said, if you're a scientist, you should definitely find a programming language to become proficient at!

Anyway, here's a start. I don't know exactly what you're trying to do, so I just hacked together a couple things from the posts I cited in my previous response. Here ya go:

use strict;
use warnings;
use List::Util qw(reduce);
use bignum;

# Number of coins to toss
my $coin_toss=1000;

# We cumulative probability of side1 appearing anywhere between 1 and 
+60 times
my $side1=60;

# Compute the binomial coefficients for row 1000 of pascal's triangle
my @triangle = robo_2(1000);

print <<EOHDR;
Tails      Count     %
-----   ----------  ------
EOHDR
my $total_prob=0;
my $runs = reduce { $a + $b } @triangle;
for (my $i = 0; $i < @triangle; $i++) {
        my $prob = $triangle[$i]/$runs;
        $total_prob += $prob unless $i > $side1;

        print "$i\t$triangle[$i]\t",100*$prob, "\n";
}

print "\n\nProbability of 0..60 tails is: ", $total_prob*100;

sub robo_2 {
        my $row = shift;
        my @cols = (1);
        ++$row;
        $cols[$_] = $cols[$_-1] * ($row-$_)/$_ for 1 .. $row-1;
        return @cols;
}
[download]

Note: The output gets pretty darned wide with 1000 tosses and bignum in the picture...

...roboticus

When your only tool is a hammer, all problems look like your thumb.

Thank you very much, this solved my problem.

By the way: I want to analyze sections of the genome encoding many genes that can be encoded either on + or - strand (as you may know, DNA is made up of two complementary strands). I'm searching for a specific kind of gene clusters which typically exhibit a strong strand bias. Therefore I want to calculate the propability, that a given strand bias occures by chance.