Back when I needed to play back sound asynchronously, I used FMOD and this sample player:

package Sound::Fmod;
use strict;
use Win32::API;

=head1 NAME

Sound::Fmod - interface to the Fmod sound library

=head1 SYNOPSIS

  use Sound::Fmod;
  my $player = Sound::Fmod->new();
  $player->init(32000, 64, 0)
    or die $player->get_error;

  my $mod = $player->load_song('../../media/invtro94.s3m')
    or die "Couldn't load song: " . $player->get_error;

  $mod->play_song();

  while (1) {
    print "...\n";
    sleep 10;
  };

=cut

sub new {
  my ($package) = @_;
  my $self = {};
  bless $self, $package;
  $self;
};

sub load_song {
  my ($self,$filename) = @_;
  warn "Loading $filename";
  my $buffer = " " x 1024;
  $buffer = $self->_load_song($filename);
  print length $buffer;
  Sound::Fmod::Song->new($buffer);
};

sub load_samples {
  my $self = shift;
  my @result;
  for my $filename (@_) {
    #$filename =~ s!/!\\!g;
    my $handle;
    if ($filename =~ /.pcm/i) {
      $handle = $self->_load_sample(-1,$filename,0x10051,0,0);
    } else {
      $handle = $self->_load_sample(-1,$filename,0x02000,0,0);
    };
    die "Couldn't load $filename :" . $self->get_error unless $handle;
    push @result, Sound::Fmod::Sample->new($handle);
  };
  @result;
};

# My own lame DLL loader, ugly hacked together
# because I'm too stupid to use Inline::C and too
# lazy to learn XS:

my $library = 'fmod';
my %functions = (
  init         => ['FSOUND_Init','LLL','L'],
  DESTROY      => ['FSOUND_Close','',''],
  _load_song   => ['FMUSIC_LoadSong','P','L'],
  _load_sample => ['FSOUND_Sample_Load','LPLLL','L'],
  get_error    => ['FSOUND_GetError','','L'],
  __PACKAGE__ . "::Song::_play_song"   => ['FMUSIC_PlaySong','L',''],
  __PACKAGE__ . "::Song::_DESTROY"     => ['FMUSIC_FreeSong','L',''],
  __PACKAGE__ . "::Sample::_play"      => ['FSOUND_PlaySound','LL','']
+,
  __PACKAGE__ . "::Sample::_DESTROY"   => ['FSOUND_Sample_Free','L',''
+],
);

# Simplicistic fudging of names
sub mangle {
  my ($name,$args) = @_;
  die "Unknown argument '$args'" unless $args =~ m!^[LP]*$!;
  my $size = (length $args) * 4;
  "_$name\@$size"
};

sub load_function {
  my ($f) = @_;
  die "Unknown function $f"
    unless exists $functions{$f};
  my @args = ('fmod.dll', @{$functions{$f}});
  $args[1] = mangle(@args[1,2]);
  my $code = Win32::API->new(@args);
  die "Couldn't load $f from fmod: $! / $^E"
    unless $code;

  no strict 'refs';
  *{$f} = sub { my $self = shift; $code->Call(@_) };
};

load_function($_)
  for keys %functions;

package Sound::Fmod::Song;
sub new {
  my ($package,$handle) = @_;
  my $self = \$handle;
  bless $self, $package;
  $self;
};

sub play_song {
  my ($self) = @_;
  $self->_play_song($$self);
};

sub DESTROY {
  my $self = shift;
  $self->_DESTROY($$self);
};

package Sound::Fmod::Sample;

sub new {
  my ($package,$handle) = @_;
  my $self = \$handle;
  bless $self, $package;
  $self;
};

sub play {
  my ($self) = @_;
  $self->_play(-1,$$self);
};

sub DESTROY {
  my $self = shift;
  $self->_DESTROY($$self);
};

1;
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I wrote it against the 3.x API - I haven't looked whether it still works with the 4.x APIs.