You mean like how Reddit works? No, not really.

You can however add nodes you like (or don't like) to your Personal Nodelet (also check your Personal Nodelet Settings). That may help achieve the effect you're looking for.

  UPDATE: Added link to Personal Nodelet Settings.
  UPDATE (Jul 14, 2011 at 1:55PM EDT): I learned something new today. See: Re^2: What did I vote for? (yes, really)