I highly recommend Dancer - it's winning. Dancer::Introduction and Dancer::Cookbook for more info. It's a minimalist framework that stays out of your way, which is what I prefer in a perl framework. I like to do things my way, and not be forced to change my coding habits too much. If you know any perl at all, and you have a solid understanding of HTTP you are golden.

Use dbicdump to auto-generate all the boring code using your database schema.
Use Dancer::Plugin::Database and DBIx::Class to get at your database (make sure to use all those modules you just auto-generated).
Dancer::Plugin::DataFu for your view.

Now add Plack and get access to all it's middlewares you might need. If you want TLS, look at tlsme.