By looking at these problems, I am not sure whether Perl with MySQL is a right way to go.

Do not misinterpret the above discussion as there being "problems" with Perl and MySQL. Nobody said there were problems with Perl and MySQL. The two work perfectly well together. The argument you see above is about using ORM's (e.g. DBIx::Class, Rose::DB::Object) which is an entirely separate issue which sparks arguments/debates/discussions like the one above. Start with Perl, DBI, and SQL, then maybe start looking at ORM's if you feel like it, try'em out, and use them if you feel that they're right for you.