Yes, you can re-compile Perl and change its INC path. If you go perl -V it will show you what the path is. You can also get the meaning of individual libraries from the %Config hash (use Config); see privlib, sitearch, sitelib, installarchlib, otherlibdirs, inc_version_list, incpath, and maybe others.

To re-configure, use the Configure script in the root of the source directory and then re-compile.