There is a big problem with encoding sequences in 2-bit format.
Whilst they occupy 1/4 the space, and are theoretically 4x faster to search, the problem is that computers only compare bytes.
With each byte holding 4 codons, you will only be able to find matches at every fourth position.
With the rise and rise of 'Social' network sites: 'Computers are making people easier to use everyday'
Examine what is said, not who speaks -- Silence betokens consent -- Love the truth but pardon error.
"Science is about questioning the status quo. Questioning authority".
In the absence of evidence, opinion is indistinguishable from prejudice.