Tk is available for ActivePerl 32 bit, not 64 bit. I suspect this is the problem although I think I mentioned it in a previous post.

Tk is a good way to go because of the huge amount of support/books etc for it. It is not being developed in new and astonishing ways, but if all you need is the basics, then I think that it is fine. I still use it, but then again, I'm not a super GUI guru.

Unless you need huge data access, 64 bit Perl gains you nothing over 32 bit Perl and you loose quite a bit in terms of support. Active State runs a bit behind the times, in the best of times, and 64 bit is not quite ready for "prime time". Consider 32 bit Perl.