perllearner007 has asked for the wisdom of the Perl Monks concerning the following question:


Hello, Is there a way to get human homologues for a mouse gene list where I get all human genes(symbols) as text output ?

Thank you
LM

Replies are listed 'Best First'.
Re: Mouse -> Human Homologues using perl
by marto (Cardinal) on Dec 09, 2011 at 17:00 UTC
Re: Mouse -> Human Homologues using perl
by Khen1950fx (Canon) on Dec 09, 2011 at 18:25 UTC
    MammalHom has some perl scripts that do exactly what you need. You can download MammalHom here:

    MammalHom.

      Thank you so much. This is exactly what I was looking for. However the I am trying to fix the script a bit since it doesn't match all the genes and leaves blank at spaces so I have to get to those entries manually but it would but great if it matched all entries. But it is a great source! Thank you!
Re: Mouse -> Human Homologues using perl
by CountZero (Bishop) on Dec 09, 2011 at 18:10 UTC
    Of course there is a way, only your question is a bit sparse on info. Please appreciate that not all Perlmonks are geneticists, so we will need some guidance from you to be able to tackle this problem.

    CountZero

    A program should be light and agile, its subroutines connected like a string of pearls. The spirit and intent of the program should be retained throughout. There should be neither too little or too much, neither needless loops nor useless variables, neither lack of structure nor overwhelming rigidity." - The Tao of Programming, 4.1 - Geoffrey James