so what have you tried ?

#!/usr/bin/perl --
use strict; use warnings;
my $input = '((113000.00 Nos.) + (250000.00 Nos.) ++ (1) )';
my $output = ' 113000.00 + 250000.00 + 1 ';
print "$input\n";
$input =~ s/ No\S+ //gx;
#~ $input =~ tr/ +//s; # squash repeating space and + characters
#~ $input =~ tr/)(//d; # delete ) and (
$input =~ tr/+ )(/+ /s; # squash repeating space and +, delete ) and (
print "$output\n";
print "$input\n";
__END__
((113000.00 Nos.) + (250000.00 Nos.) ++ (1) )
 113000.00 + 250000.00 + 1
 113000.00 + 250000.00 + 1
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