Tk doesn't look too great

Tk only looks as good as the effort you put into the various color and font settings. If you want something that respects the system style settings in windows, you can try Gtk2. See Camelbox: A build of Gtk2-Perl for Windows or if you desire

From: Gabor Szabo <szabgab@gmail.com>

For ActiveState users

* I assume you already have ActiveState Perl installed on your system.
If not, download and install ActiveState Perl from
http://activestate.com/Products/ActivePerl/

* Next you need to install the GTK+ 2.x.x runtime environment. The
latest version can be downloaded from
http://gimp-win.sourceforge.net/stable.html

* Ensure that the <INSTALL_PATH>\GTK\2.0\bin directory is in your
PATH after this installation.

* Next you need to install the Win32 binary packages for gtk2-perl.
Download and install the latest version of Gtk2.ppd and Glib.ppd from
http://gtk2-perl.sourceforge.net/win32/ppm/
(Another way to install these ppds is as follows
C:\Temp> ppm install http://gtk2-perl.sourceforge.net/win32/ppm/Gtk2.p
+pd
C:\Temp> ppm install http://gtk2-perl.sourceforge.net/win32/ppm/Glib.p
+pd
)

Your system should be ready to roll !
[download]

There is a very good tutorial at Gtk2 Study Guide. Plus you can google for numerous others. Wx is object oriented like C++, whereas Gtk2 is more like C ( and Perl ) :-) Me ducks.