I took this:

$_ = qq{133.133.133.133, 87.87.87.87 127.0.0.1 - - [21/Apr/2012:04:35:
+01 +0200] "GET /seo/vbseocp.php HTTP/1.0" 404 300 "-" "Internet Explo
+rer 6.0" 95.95.95.95, 87.87.87.87 127.0.0.1 - - [22/Apr/2012:04:00:43
+ +0200] "GET / HTTP/1.0" 200 10211 "http://yandex.ru/yandsearch?text=
+example.com" "Mozilla/4.0 (compatible; MSIE 6.0; Windows NT 5.1; SV1;
+)"};


m/^(\S+)\, (\S+) (\S+) \- \- \[(\d{2})\/(\w+)\/(\d{4})\:(\d{2})\:(\d{2
+})\:(\d{2})\+(\d{4})\] \"\S+\" (\d{3}) (\d+|-) \"(.*?)\" \"\.*?\"$/;

print map { "[$_]\n" } $1,$2,$3,$4,$5,$6,$7,$8,$9,$10,$11,$12,$13;
[download]

And tweaked your expression down to this:

m@^(\S+?), (\S+) (\S+) - - \[(\d{2})/(\w+)/(\d{4}):\s*(\d{2}):(\d{2}):
+\s*(\d{2}) \+(\d{4})\] ".*?" (\d{3}) (\d+) "(.*?)" "(.*?)"@;
#      1                                           2                  
+3                         4            5              6   7
[download]

1. I made \S non-greedy, to not gobble up the comma.
2. I changed one literal space to \s* (Your example doesn't have spaces.)
3. Same as #2.
4. I changed "greedy non-whitespace" (which was failing b/c the string within has whitespace) to "non-greedy non-quotes"
5. I don't know what you intended with "(\d+|-)"...
6. Again, non-greedy non-quotes - I think that's what you wanted.
7. I removed the end-of-line anchor ($), because you aren't currently matching to the end.

Also note I changed the delimiter to something NOT in your content, so it doesn't need to be escaped. And I did NOT escape these other characters: -:"

Update: My numbered notes line up if you click 'download'.