Both ImageMagick and GD are compatible with perl 5.10.

If you have ImageMagick installed on your system you can run it like this:

my $imageMagick =         "C:/Phil/ImageMagick-6.7.3-Q16/convert.exe";
+  # Convert images

say for qx($imageMagick \"$source\" -resize x$Y $\"target\");
[download]

You can find extensive documentation at: http://www.imagemagick.org/script/command-line-options.php

GD is also excellent. You might try GD::Simple first.

I would suggest you spend time initially with ImageMagick due to its very broad applicability, deep documentation base, and exhaustive list of examples, and then move to GD in the (unlikely) event that you cannot find a solution to a specific problem.