in reply to Best way to Download and Process a XML file
150 GB? Ouch.
AnyEvent::HTTP should allow you to issue an HTTP request, and process it a chunk at a time, while it arrives, without having to save it anywhere.
And XML::Twig can parse XML chunk by chunk.
Pairing the two you ought to be able to do this without temporary files. Exactly how to do it, I can't help you. I have limited experience with AnyEvent::HTTP; and virtually none with XML::Twig.
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