Not sure it applies to your situation, but you may want to look at the ProxyPass ProxyPassReverse directives in Apache

see also mod_proxy ( eg : http://marc.info/?l=apache-modperl&m=115557308908428&w=2). You can search the archives of mod_perl's users list on these subjects (http://perl.apache.org/maillist/modperl.html). After you've done a little research, you'll get good answers on that list too.