Yes. The Win32::OLE module allows you to manipulate Word using the COM interface that it exposes. In other words, you'll need to understand the Word object model, and a little bit of COM in general. If you've written VBA macros for Word (or Excel or ....) you've gotten the flavor.

There are some good resources here in the monastery. cacharbe has written a very good tutorial on using the Win32::OLE interface to Excel, which can help to get you started. You can also look up more resources and tutorials on Dave Roth's web site.