I think the error message is pretty self-explanatory. Some quick Googling shows that the "HOMER Installation Guide" describes that one should download configureHomer.pl, save it in the directory where you would like the software to be installed (such as /home/username/homer), and then run perl /home/username/homer/configureHomer.pl -install. It looks like that script writes the config.txt file.

In reply to Re: could not open configuration file by haukex
in thread could not open configuration file by yueli711

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