Without having benchmarked it, I have a feeling that your lookahead regex will fail faster if it's anchored: 
/^(?=.*a)(?=.*e)(?=.*i)(?=.*o)(?=.*u)/i

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In reply to Re: Re: regex testing for ALL of the vowels in a scalar by ysth
in thread regex testing for ALL of the vowels in a scalar by D'Oh!!

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