I'm going out on a limb here and assume you don't want that Whois info everybody is talking aboot. Best way to go about it then is to use any of the HTML::Parser based modules (HTML::TokeParser, HTML::SimpleParse, HTML::Tree, etc) together with LWP::Simple/LWP::UserAgent. If you provide us with more, solid details on what you wanna do, I'm sure some of us will cook up something nice for you.
Greetz
Beatnik
...Perl is like sex: if you're doing it wrong, there's no fun to it.