Take a look at http://search.cpan.org - a cursory scan turned up SerialPort.
Wiser Monks than I might offer code examples if you provide some details on what you want to accomplish.
    cheers,
    ybiC

In reply to RE: Interfacing instruments... serial, parallel ports, Perl (CPAN mods) by ybiC
in thread Interfacing Instruments through serial port and parllel port through PERL by Anonymous Monk

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