I'd write that as (untested): 
$$text_ref =~ s{"http://\K([^/"]*)(?=["/]){$main::fixers{$1} // $1}eg;

[download]
I assume non of the values of %main::fixers is undefined.

In reply to Re: Replace after match in regex (key value subsitution) by JavaFan
in thread Replace after match in regex (key value subsitution) by brycen

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