Oh, that's easy.

use Magick::Software;
no strict;
Magick::Software->enable_esp(1);
Magick::Software->disable_specifications(1);

Magick::Software->dwiw( how_much => '$5,000 worth',
                        how_hard => 'pretty complex' );
[download]

But seriously, you can do what you want with raw DBI, a good ORM like DBIx::Class, and a JavaScript library with excellent CSS/plugins or nice prefab UI like ExtJS. There are also a few modules to use and manipulate Excel and Excel-like records. A good web framework (Catalyst, Dancer, Mojolicious...) will make it all fairly easy to hang together.

Your question as it stands is entirely too vague to help you beyond similar generalizations.